Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes
نویسندگان
چکیده
منابع مشابه
Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes.
BACKGROUND Previous efforts to preserve β cell function in individuals with type 1 diabetes (T1D) have focused largely on the use of single immunomodulatory agents administered within 100 days of diagnosis. Based on human and preclinical studies, we hypothesized that a combination of low-dose anti-thymocyte globulin (ATG) and pegylated granulocyte CSF (G-CSF) would preserve β cell function in p...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2014
ISSN: 0021-9738
DOI: 10.1172/jci78492